The Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) is a computer program that is used to calculate the risks of breast and ovarian cancer in women based on their family history. It is also used to calculate the probability that they are carriers of cancer-associated mutations in the BRCA1 or BRCA2 gene. The latest version of BOADICEA (BWA v3) is described by Lee et al. (2013). You can run BOADICEA risk calculations using the BOADICEA Web Application. This program is free for anyone to use, including researchers, healthcare professionals and members of the public. To access this software, all you need is a BOADICEA is a user account, which you can setup online in a minutes here. To date, more than 3300 healthcare professionals have registered to use the BOADICEA Web Application, and it is used in more than 60 countries worldwide. In the United Kingdom, it is recommended as a risk assessment tool in the National Institute for Health and Care Excellence clinical guideline CG164 and has been incorporated in the guidelines of several countries for the management of familial breast cancer. The BOADICEA Web Application is an example of translational research, where scientific software has been developed into a tool for healthcare professionals.

For further information on BOADICEA please contact Dr Alex Cunningham or Dr Antonis Antoniou.