Reader in Molecular Cancer Genetics
Tel. +44 (0)1223 761930
Dr Dunning has 25 years experience as a laboratory scientist in the genetic epidemiology of common diseases – formerly studying cardiovascular disease and more recently cancer. Her principle role, within her team is to link the science of genetic epidemiologiy with the technological capabilities of the High-throughput Laboratory in the Centre.
Currently, the main research themes within the laboratory are post Genome-wide Association Studies (GWAS) confirmation and follow-up studies. These include Fine Scale Mapping projects, which aim to identify the directly causative variants within genomic loci discovered via GWAS. Skills we learned during the initial Breast Cancer GWAS are now being applied to other traits and diseases – specifically: Susceptibility to Endometrial Cancer, Melanoma and naevus count; Differences in response of normal tissues to Radiotherapy – the RAPPER project; Genetic control of mean telomere length and its effect on cancer susceptibility – the Telomeres project.