The main purpose of the study is to determine how normal, common genetic variation affects cancer risk. We hope to achieve this by collecting a blood sample and information on family history and lifestyle from men and women in East Anglia who have been diagnosed with specific cancers.
The research aims to find out:
- How often cancer occurs in a person with a family history of that cancer.
- Whether there are any ‘low risk genes’ for each type of cancer. This will help us find out if normal human genetic variation influences the risk of developing cancer. In other words, is a person’s genetic makeup important in determining risk?
- If a person’s genetic makeup influences the way they respond to treatment for cancer.
- How a person’s genetic makeup interacts with lifestyle and environment factors.