The Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) is a computer program that is used to calculate the risks of breast and ovarian cancer in women based on their family history. It is also used to calculate the probability that they are carriers of cancer-associated mutations in the BRCA1 or BRCA2 gene. To access BOADICEA, all you need is a BOADICEA is a user account, which you can setup online in a minutes here.
You can access two different versions of the BOADICEA program using the links in the menu to the left:
(i) BWA v3 considers the explicit effects of BRCA1 and BRCA2 mutations;
(ii) BWA v4 Beta considers the explicit effects of BRCA1, BRCA2, PALB2, CHEK2 and ATM mutations.
This tool is provided for research use only. The BOADICEA software is at an early stage of development and is provided “as is” (ie. it is not error-free). BOADICEA is designed for research use only and is not designed for providing information on which to base clinical decisions. BOADICEA has not been approved for use by any regulatory authority.
BWA v4 Beta is not for commercial use. We are now licensing BOADICEA V5 for commercial use. BOADICEA V5 is the first comprehensive breast cancer risk prediction model using information on rare genetic variants in high- and moderate-risk cancer susceptibility genes, Polygenic Risk Scores, family history and other lifestyle or hormonal risk factors for breast cancer.
Please note: we have now released the CanRisk Tool – new software based on BOADICEA V5 here: https://www.canrisk.org