The study received Multi-Centre Research Ethics Committee (MREC) approval in July 1998 from the Anglia and Oxford MREC. We have been awarded a 5 year grant from Cancer Research UK until January 2022.  Further details of the study can be found on the Cancerhelp website.

• To date (01 May 2019), 11351 recruits have provided a baseline questionnaire and 10657 recruits have provided a baseline blood sample.
• The response rate to 2, 5 and 10-year follow-up is over 75%.